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Medication that inhibit CYP2D6 exercise, for instance paroxetine and quinidine, may possibly trigger reduced clearance of oxycodone which could lead on to an increase in oxycodone plasma concentrations. Concurrent administration of quinidine resulted in a rise in oxycodone Cmax by 11%, AUC by 13%, and t½ elim.As with all opioid preparations, oxyco
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